Drug Standards
Apexbio Technology LLC Enalaprilat Dihydrate 84680-54-6 50mg
Enalaprilat Dihydrate is a small-molecule inhibitor targeting angiotensin-converting enzyme (ACE) It is designed to inhibit ACE thereby blocking the conversion of angiotensin I to the potent vasoconstrictor angiotensin II and reducing vascular resistance and blood pressure Enalaprilat Dihydrate exerts its biological activity primarily through competitive binding to the active site of ACE It demonstrates high potency and specificity with an inhibitory concentration (IC50) value in the low nanomolar range Based on these pharmacological properties Enalaprilat Dihydrate holds research potential in studies of ACE inhibition mechanisms cardiovascular physiology and drug discovery targeting hypertension-related pathologies
Apexbio Technology LLC Diphenhydramine HCl 147-24-0 10mM (in 1mL DMSO)
Diphenhydramine HCl is a small-molecule antagonist targeting histamine H1 receptors It is designed to competitively inhibit histamine binding to H1 receptors in peripheral tissues and the central nervous system thereby suppressing histamine-mediated hypersensitivity responses Diphenhydramine HCl exerts its biological activity primarily through antagonism of histamine H1 receptors and also exhibits anticholinergic activity within the central nervous system Based on these pharmacological properties Diphenhydramine HCl holds research potential in the study of allergic reactions sleep regulation sedation pathways motor disorders cognitive function memory processes and investigations of cholinergic and histaminergic neurotransmission
Apexbio Technology LLC Fluconazole hydrate 155347-36-7 1g
Fluconazole hydrate (CAS 155347-36-7) is a small-molecule inhibitor targeting the fungal enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and arresting fungal growth Fluconazole hydrate exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies fluconazole hydrate demonstrates inhibitory activity with documented IC50 values typically ranging from 0 1 to 10 g/mL depending on fungal strain and experimental conditions Based on these pharmacological properties fluconazole hydrate holds research potential in antifungal pharmacology assays fungal infection model studies and evaluation of combinational antifungal therapies
Apexbio Technology LLC Amoxicillin Sodium 34642-77-8 5g
Amoxicillin Sodium (CAS 34642-77-8) is a small-molecule inhibitor targeting bacterial cell wall biosynthesis It is designed to disrupt peptidoglycan formation thereby compromising bacterial cell wall integrity Amoxicillin Sodium exerts its biological activity primarily through inhibition of peptidoglycan biosynthesis leading to bacterial lysis and cell death In in vitro studies Amoxicillin Sodium demonstrates broad-spectrum antibacterial inhibitory activity with IC50 values ranging from 0 1 g/mL to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties Amoxicillin Sodium holds research potential in bacterial physiology characterization antibiotic resistance evaluations and in vitro infection modeling studies
Apexbio Technology LLC Ethacrynic Acid 58-54-8 200mg
Ethacrynic acid (CAS 58-54-8) is a small molecule loop diuretic that exerts its effects by inhibiting the Na sup /sup -K sup /sup -2Cl sup /sup cotransporter (NKCC2) localized in the thick ascending limb of the loop of Henle This inhibition interrupts reabsorption of sodium potassium and chloride ions leading to increased concentrations of these electrolytes in the renal tubular fluid and decreased medullary osmolarity As a result water reabsorption is reduced promoting diuresis and subsequent urinary excretion Ethacrynic acid is frequently utilized in research investigating renal function electrolyte transport mechanisms and pathophysiology of edematous states including heart failure nephrotic syndrome and hepatic conditions
Apexbio Technology LLC Metoprolol Succinate 98418-47-4 50mg
Metoprolol Succinate (CAS 98418-47-4) is an orally active selective 1-adrenergic receptor antagonist By selectively inhibiting 1-receptors in cardiac tissue it modulates myocardial contractility and heart rate resulting in altered hemodynamic parameters In preclinical cardiovascular models this small molecule is utilized to investigate its effects on cardiac function and systemic blood pressure Owing to its receptor selectivity Metoprolol Succinate is commonly employed in studies exploring therapeutic strategies for chronic heart failure and hypertension
Sigma Aldrich Fine Chemicals Biosciences 1-Dodecanol reagent grade, 98% | 112-53-8 | MFCD00004753 | 500G
1-Dodecanol reagent grade, 98% | Purity: 98% | Mol Wt: 186.33 | 112-53-8 | MFCD00004753 | 500G
Sigma Aldrich Fine Chemicals Biosciences Sodium salicylate European Pharmacopoeia (EP) Reference Standard | 54-21-7 | MFCD00002440 |
Sodium salicylate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 160.1 | 54-21-7 | MFCD00002440 |
Sigma Aldrich Fine Chemicals Biosciences Orphenadrine Related Compound C United States Pharmacopeia (USP) Reference Standard | 10488-36-5 | 20MG
Orphenadrine Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 291.82 | 10488-36-5 | 20MG
Sigma Aldrich Fine Chemicals Biosciences Lometrexol hydrate >=95% (HPLC) | 106400-81-1 (anhydrous) | 5MG
Lometrexol hydrate >=95% (HPLC) | Purity: >=95% (HPLC) | 106400-81-1 (anhydrous) | 5MG